The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2011

Filed:

Mar. 08, 2004
Applicants:

Kai Schiemann, Seeheim-Jugenheim, DE;

Henning Böttcher, Darmstadt, DE;

Timo Heinrich, Gross-Umstadt, DE;

Günter Hölzemann, Seeheim-Jugenheim, DE;

Christoph Van Amsterdam, Darmstadt, DE;

Gerd Bartoszyk, Weiterstadt, DE;

Joachim Leibrock, Pfungstadt, DE;

Christoph Seyfried, Seeheim-Jugenheim, DE;

Inventors:

Kai Schiemann, Seeheim-Jugenheim, DE;

Henning Böttcher, Darmstadt, DE;

Timo Heinrich, Gross-Umstadt, DE;

Günter Hölzemann, Seeheim-Jugenheim, DE;

Christoph Van Amsterdam, Darmstadt, DE;

Gerd Bartoszyk, Weiterstadt, DE;

Joachim Leibrock, Pfungstadt, DE;

Christoph Seyfried, Seeheim-Jugenheim, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); C07D 403/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Chromenoneindole derivatives of the formula (I), in which R, R, R, R, A and B are as defined in Claim, and pharmaceutically usable prodrugs, derivatives, solvates, stereoisomers and salts thereof, exhibit particular actions on the central nervous system, in particular 5-HT reuptake-inhibiting and 5-HT-agonistic and/or -antagonistic actions. They are distinguished by particularly high bioavailability and particularly high inhibition of 5-HT reuptake.


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