The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2011
Filed:
Aug. 14, 2007
Gary Mcmaster, Ann Arbor, MI (US);
Joan Davies, Los Gatos, CA (US);
Yunqing MA, Cupertino, CA (US);
Yuling Luo, San Ramon, CA (US);
Gary McMaster, Ann Arbor, MI (US);
Joan Davies, Los Gatos, CA (US);
Yunqing Ma, Cupertino, CA (US);
Yuling Luo, San Ramon, CA (US);
Other;
Abstract
This invention provides methods of quantitating nucleic acids from problematic samples, such as aged samples, formalin fixed samples, paraffin embedded samples, samples with aneuploid cells, and cells with fragmented nucleic acids. Methods include techniques to efficiently solublize the nucleic acids under non-denaturing conditions from preserved clinical samples without resort to organic extractions, to normalize cell counts regardless of aneuploidy, to access the fragmentation state of the nucleic acids, and to provide standard curves for degraded nucleic acid samples.