The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2011
Filed:
Feb. 04, 2009
Timothy Foster, Dublin, IE;
Fiona Roche, Dublin, IE;
Mark Pallen, Malvern, GB;
Joseph M. Patti, Cumming, GA (US);
Jeff T. Hutchins, Cumming, GA (US);
Pietro Speziale, Pavia, IT;
Timothy Foster, Dublin, IE;
Fiona Roche, Dublin, IE;
Mark Pallen, Malvern, GB;
Joseph M. Patti, Cumming, GA (US);
Jeff T. Hutchins, Cumming, GA (US);
Pietro Speziale, Pavia, IT;
Universita'Degli Studi Di Pavia, Pavia, IT;
Inhibitex, Inc., Alpharetta, GA (US);
Provost Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin, Dublin, IE;
Abstract
Surface proteins are provided which generate polyclonal and monoclonal antibodies which are cross-reactive to both coagulase-positivebacteria, such asand to coagulase-negative bacteria, such asand. The antibodies may be generated from surface proteins that have been isolated on the basis of characteristics that may be common betweenand coagulase-negative staphylococci, or the A domains of those surface proteins, and these recombinant surface proteins are used to generate the cross-reactive antibodies. Vaccines comprising an immunologically effective amount of the proteins are also provided, and these vaccines are used in methods for the treatment or protection against a wide variety of staphylococcal infections.