The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2011
Filed:
May. 31, 2006
Patrick Bäuerle, Gauting, DE;
John Lumsden, München, DE;
Stefan Pflanz, Redwood City, CA (US);
Tobias Raum, München, DE;
Jörg Volkland, Neuried, DE;
Patrick Bäuerle, Gauting, DE;
John Lumsden, München, DE;
Stefan Pflanz, Redwood City, CA (US);
Tobias Raum, München, DE;
Jörg Volkland, Neuried, DE;
Micromet AG, Munich, DE;
Abstract
The invention relates to a humanized monoclonal antibody or fragment thereof which specifically binds to human interlukin-2 (IL2), whereby said humanized monoclonal antibody neutralizes the activity of human IL2 by binding to the human IL2 prior to, during, and/or subsequent to the binding of the human IL2 to the human IL2-receptor, and wherein the light chain variable region of the humanized monoclonal antibody comprises in its second framework region the contiguous amino acid sequence KAPKA at amino acid positions 42-46.