The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7964637 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 21, 2011

Filed:

Sep. 08, 2006
Applicants:

Makoto Harada, Hiratsuka, JP;

Hiroyuki Matsuda, Kanagawa, JP;

Kenya Ishida, Kanagawa, JP;

Yuichiro Yamazaki, Hiratsuka, JP;

Inventors:

Makoto Harada, Hiratsuka, JP;

Hiroyuki Matsuda, Kanagawa, JP;

Kenya Ishida, Kanagawa, JP;

Yuichiro Yamazaki, Hiratsuka, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/335 (2006.01); C07D 307/94 (2006.01);
U.S. Cl.
CPC ...
Abstract

A simplified production method of stereoisomer of theaspiran having high optical purity has been desired. An alcohol compound having a specific skeleton is enantioselectively esterified with an enzyme, or an ester compound having a specific skeleton is enantioselectively hydrolyzed with an enzyme. The resultant optically active ester or optically active alcohol is used. Thus, optically active theaspiran having a desired configuration and having a high optical purity is obtained in a satisfactory yield.


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