The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 21, 2011

Filed:

Jan. 25, 2007
Applicants:

Richard R. Tidwell, Pittsboro, NC (US);

David W. Boykin, Atlanta, GA (US);

W. David Wilson, Atlanta, GA (US);

Reto Brun, Therwil, CH;

Laixing HU, Decatur, GA (US);

Karl Werbovetz, Worthington, OH (US);

Mohamed A. Ismail, Atlanta, GA (US);

Reem K. Arafa, Cairo, EG;

Inventors:

Richard R. Tidwell, Pittsboro, NC (US);

David W. Boykin, Atlanta, GA (US);

W. David Wilson, Atlanta, GA (US);

Reto Brun, Therwil, CH;

Laixing Hu, Decatur, GA (US);

Karl Werbovetz, Worthington, OH (US);

Mohamed A. Ismail, Atlanta, GA (US);

Reem K. Arafa, Cairo, EG;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed herein are novel dicationic teraryl compounds and their aza analogues, including compounds of Formula (IIe): wherein p and q are each 0 and each A, Y and Z is CR. An exemplary compound of Formula (IIe) is: Methods for combating microbial infections, such as parasiticspecies, with novel dicationic terphenyl compounds and their aza analogues are included. Processes for synthesizing novel dicationic terphenyl compounds and their aza analogues are disclosed along with methods for evaluation of the compounds as potential anti-protozoan agents.


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