The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 21, 2011

Filed:

Oct. 04, 2005
Applicants:

Robert W. Mahley, San Francisco, CA (US);

Karl H. Weisgraber, Walnut Creek, CA (US);

Yadong Huang, San Francisco, CA (US);

Inventors:

Robert W. Mahley, San Francisco, CA (US);

Karl H. Weisgraber, Walnut Creek, CA (US);

Yadong Huang, San Francisco, CA (US);

Assignee:

The J. David Gladstone Institutes, San Francisco, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 31/42 (2006.01); A61K 31/38 (2006.01); A01N 43/76 (2006.01); A01N 43/12 (2006.01); C07D 498/00 (2006.01); C07D 487/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds that inhibit apoE4 domain interaction; and compositions, including pharmaceutical compositions, comprising the compounds. The present invention provides methods of treating apoE4-related disorders. The methods generally involve administering to an individual in need thereof a therapeutically effective amount of an apoE4 domain interaction inhibitor.


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