The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 21, 2011

Filed:

Aug. 21, 2009
Applicants:

Rahul C. Mehta, San Marco, CA (US);

Gregory E. Hardee, Rancho Santa Fe, CA (US);

Phillip Dan Cook, Fallbrook, CA (US);

David J. Ecker, Encinitas, CA (US);

Yali Jennifer Tsai, La Jolla, CA (US);

Michael V. Templin, Carlsbad, CA (US);

Inventors:

Rahul C. Mehta, San Marco, CA (US);

Gregory E. Hardee, Rancho Santa Fe, CA (US);

Phillip Dan Cook, Fallbrook, CA (US);

David J. Ecker, Encinitas, CA (US);

Yali Jennifer Tsai, La Jolla, CA (US);

Michael V. Templin, Carlsbad, CA (US);

Assignee:

Isis Pharmaceuticals, Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 31/70 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compositions and methods which enhance the delivery of oligonucleotides and other nucleosidic moieties via topical routes of administration. Preferred compositions include liposomes or penetration enhancers for the delivery of such moieties to dermal and/or epidermal tissue in an animal for investigative, therapeutic or prophylactic purposes.


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