The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 21, 2011

Filed:

Aug. 03, 2007
Applicants:

Svetlana O. Doronina, Snohomish, WA (US);

Peter D. Senter, Seattle, WA (US);

Brian E. Toki, Shoreline, WA (US);

Allen J. Ebens, San Carlos, CA (US);

Toni Beth Kline, Seattle, WA (US);

Paul Polakis, Burlingame, CA (US);

Mark X. Sliwkowski, San Carlos, CA (US);

Susan D. Spencer, Tiburon, CA (US);

Inventors:

Svetlana O. Doronina, Snohomish, WA (US);

Peter D. Senter, Seattle, WA (US);

Brian E. Toki, Shoreline, WA (US);

Allen J. Ebens, San Carlos, CA (US);

Toni Beth Kline, Seattle, WA (US);

Paul Polakis, Burlingame, CA (US);

Mark X. Sliwkowski, San Carlos, CA (US);

Susan D. Spencer, Tiburon, CA (US);

Assignee:

Seattle Genetics, Inc., Bothell, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/02 (2006.01); C07K 2/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Auristatin peptides, including MeVal-Val-Dil-Dap-Norephedrine (MMAE) and MeVal-Val-Dil-Dap-Phe (MMAF), were prepared and attached to Ligands through various linkers, including maleimidocaproyl-val-cit-PAB. The resulting ligand drug conjugates were active in vitro and in vivo.


Find Patent Forward Citations

Doronina, Svetlana. (2011). Monomethylvaline compounds capable of conjugation to ligands (U.S. Patent No. 7964566). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7964566

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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