The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2011
Filed:
May. 10, 2002
Masaki Hirashima, Kumamoto-ken, JP;
Takeshi Naruse, Kumamoto-ken, JP;
Hiroaki Maeda, Kumamoto-ken, JP;
Chikateru Nozaki, Kumamoto-ken, JP;
Takeshi Goto, Tsukuba, JP;
Katsuhiko Akiyama, Tsukuba, JP;
Wataru Hattori, Tsukuba, JP;
Masaki Hirashima, Kumamoto-ken, JP;
Takeshi Naruse, Kumamoto-ken, JP;
Hiroaki Maeda, Kumamoto-ken, JP;
Chikateru Nozaki, Kumamoto-ken, JP;
Takeshi Goto, Tsukuba, JP;
Katsuhiko Akiyama, Tsukuba, JP;
Wataru Hattori, Tsukuba, JP;
Juridical Foundation The Chemo-Sero-Therapeutic Research Institute, Kumamoto-Shi, JP;
Hisamitsu Pharmaceutical Co., Inc., Tosu-Shi, JP;
Abstract
A peptide fragment or a series of peptide fragments containing one or more selenocysteine that has a lowered toxicity than selenocystine and that exhibits a cytotoxicity-inhibitory activity. The peptide fragment or a series of peptide fragments according to the present invention has preferably the amino acid sequence from 260th to 362nd amino acid residues from the C-terminal of selenoprotein P, or said amino acid sequence with one or several amino acid residues therein being deleted, substituted or added, or a partial sequence of either of the above amino acid sequences, or an amino acid sequence comprising as a part any of the above amino acid sequences. A screening method for a peptide fragment having the cytotoxicity-inhibitory activity is also provided.