The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2011

Filed:

Feb. 17, 2006
Applicants:

Steven P. Govek, San Diego, CA (US);

Jean-michel Vernier, Laguna Niguel, CA (US);

Theodore Kamenecka, Palm Beach Gardens, NJ (US);

John H. Hutchinson, La Jolla, CA (US);

Richard Pracitto, North Wales, PA (US);

Inventors:

Steven P. Govek, San Diego, CA (US);

Jean-Michel Vernier, Laguna Niguel, CA (US);

Theodore Kamenecka, Palm Beach Gardens, NJ (US);

John H. Hutchinson, La Jolla, CA (US);

Richard Pracitto, North Wales, PA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); A61K 31/4192 (2006.01); C07D 403/12 (2006.01); C07D 249/20 (2006.01); C07D 249/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to benzazole compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.


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