The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2011

Filed:

Mar. 24, 2009
Applicants:

Jason S. Newcom, Northford, CT (US);

Stephen J. O'connor, Guilford, CT (US);

Gary R. Gustafson, Ridgefield, CT (US);

Inventors:

Jason S. Newcom, Northford, CT (US);

Stephen J. O'Connor, Guilford, CT (US);

Gary R. Gustafson, Ridgefield, CT (US);

Assignee:

Cara Therapeutics, Inc., Shelton, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 487/04 (2006.01); A61K 31/5365 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides compounds having the structure of formula I, and prodrugs, stereoisomers, racemates, salts, hydrates, solvates, acid salt hydrates and isomorphic crystalline forms thereof, wherein A, Y and the groups R, R, Rand Rare defined in the specification. These compounds can be administered in pharmaceutical formulations to modulate cannabinoid receptor activity for the prevention and treatment of a variety of diseases and conditions, including pain, inflammation and pruritis.


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