The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2011

Filed:

Jul. 29, 2004
Applicants:

Jozsef Barkoczy, Budapest, HU;

Istvan Ling, Budapest, HU;

Gyula Simig, Budapest, HU;

Gabor Szenasi, Budapest, HU;

Gabor Gigler, Budapest, HU;

Szabolcs Kertesz, Budapest, HU;

Gyula Szücs, Budapest, HU;

Geza Szabo, Budapest, HU;

Miklos Vegh, Budapest, HU;

Laszlo Gabor Harsing, Budapest, HU;

Inventors:

Jozsef Barkoczy, Budapest, HU;

Istvan Ling, Budapest, HU;

Gyula Simig, Budapest, HU;

Gabor Szenasi, Budapest, HU;

Gabor Gigler, Budapest, HU;

Szabolcs Kertesz, Budapest, HU;

Gyula Szücs, Budapest, HU;

Geza Szabo, Budapest, HU;

Miklos Vegh, Budapest, HU;

Laszlo Gabor Harsing, Budapest, HU;

Assignee:

Egis Gyogyszergyar Rt., Budapest, HU;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 9/10 (2006.01); A61K 31/55 (2006.01); C07D 243/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to new 8-chloro-2,3-benzodiazepine derivatives of the general formula (I), wherein R stands for a lower alkyl group or a group of the general formula —NH—R', wherein R′ stands for a lower alkyl or a lower cycloalkyl group), and pharmaceutically acceptable acid addition salts thereof. The invention also encompasses a process for the preparation of said compounds, pharmaceutical compositions containing them and new intermediates useful for the preparation of the new 8-chloro-2,3-benzodiazepine derivatives. The compounds according to the invention possess AMPA/kainate receptor inhibiting activity.


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