The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2011

Filed:

May. 17, 2005
Applicants:

Dennis Klinman, Potomac, MD (US);

Daniela Verthelyi, Potomac, MD (US);

Ken Ishii, Rockville, MD (US);

James J. Mond, Silver Spring, MD (US);

Mayda Gursel, Rockville, MD (US);

Inventors:

Dennis Klinman, Potomac, MD (US);

Daniela Verthelyi, Potomac, MD (US);

Ken Ishii, Rockville, MD (US);

James J. Mond, Silver Spring, MD (US);

Mayda Gursel, Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/38 (2006.01); A61K 45/00 (2006.01); A61K 47/00 (2006.01); A61K 31/70 (2006.01); A61K 9/127 (2006.01); A01N 43/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

D type CpG oligodeoxynucleotides are provided herein that include a sequence represented by the following formula:5' XXXPuPyCpG PuPyXXX(W)(G)-3′wherein the central CpG motif is unmethylated, Pu is a purine nucleotide, Py is a pyrimidine nucleotide, X and W are any nucleotide, M is any integer from 0 to 10, and N is any integer from 4 to 10. Methods of using these oligodeoxynucleotides to induce an immune response are provided.


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