The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2011
Filed:
Jun. 29, 2007
Zoran Popovic, Münster, DE;
Manuel Matthias Tsotsalas, Düsseldorf, DE;
Michael Busby, Münster, DE;
Luisa DE Cola, Müunster, DE;
Gion Calzaferri, Bern, CH;
Hans-peter Josel, Weilheim, DE;
Zoran Popovic, Münster, DE;
Manuel Matthias Tsotsalas, Düsseldorf, DE;
Michael Busby, Münster, DE;
Luisa De Cola, Müunster, DE;
Gion Calzaferri, Bern, CH;
Hans-Peter Josel, Weilheim, DE;
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Universitaet Bern, Bern, CH;
Abstract
A conjugate comprising a dye-labeled microporous crystal, a stop-cock moiety, and covalently bound thereto an affinity binding agent is disclosed. The dye-labeled microporous crystal is a zeolite crystal, such as a zeolite L crystal, having a large number of channels in its interior into which the dye is loaded. The stop-cock moiety can be functionalized with an amino group to which a carboxyester group can be attached. The affinity binding agent allows for the binding to a biological moiety. The conjugate of the moiety can be used in in-vivo and/or in-vitro imaging applications.