The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2011
Filed:
Apr. 08, 2009
Yun Yen, Arcadia, CA (US);
David Horne, Altadena, CA (US);
Yate-ching Yuan, Arcadia, CA (US);
Bing-sen Zhou, West Covina, CA (US);
Angela L Perkins Harki, Minneapolis, MN (US);
Leila Su, Diamond Bar, CA (US);
Yun Yen, Arcadia, CA (US);
David Horne, Altadena, CA (US);
Yate-Ching Yuan, Arcadia, CA (US);
Bing-Sen Zhou, West Covina, CA (US);
Angela L Perkins Harki, Minneapolis, MN (US);
Leila Su, Diamond Bar, CA (US);
City of Hope, Duarte, CA (US);
Abstract
Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme. These inhibitors may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases.