The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2011

Filed:

Mar. 30, 2005
Applicants:

Hitoshi Arai, Nishinomiya, JP;

Tsutomu Matsumura, Sakai, JP;

Syoichi Isami, Susono, JP;

Hiroshi Ishida, Sunto-gun, JP;

Koji Hagihara, Sakai, JP;

Hiroshi Umehara, Sunto-gun, JP;

Yoshinori Yamashita, Sunto-gun, JP;

Nana Oiwa, Sunto-gun, JP;

Yukimasa Shiotsu, Sunto-gun, JP;

Tomoki Naoe, Aichi, JP;

Hitoshi Kiyoi, Aichi, JP;

Inventors:

Hitoshi Arai, Nishinomiya, JP;

Tsutomu Matsumura, Sakai, JP;

Syoichi Isami, Susono, JP;

Hiroshi Ishida, Sunto-gun, JP;

Koji Hagihara, Sakai, JP;

Hiroshi Umehara, Sunto-gun, JP;

Yoshinori Yamashita, Sunto-gun, JP;

Nana Oiwa, Sunto-gun, JP;

Yukimasa Shiotsu, Sunto-gun, JP;

Tomoki Naoe, Aichi, JP;

Hitoshi Kiyoi, Aichi, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 471/22 (2006.01); C07D 487/04 (2006.01); C07D 239/70 (2006.01); C07D 471/00 (2006.01); C07D 487/00 (2006.01); C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 405/00 (2006.01); C07D 409/00 (2006.01); C07D 411/00 (2006.01); C07D 413/00 (2006.01); C07D 417/00 (2006.01); C07D 419/00 (2006.01); A61K 31/505 (2006.01); A01N 43/56 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides an antitumor agent and the like, which comprises as an active ingredient, a pyrimidine derivative represented by Formula (I): [wherein —X—Y—Z— represents —O—CR═N— (wherein Rrepresents a hydrogen atom, a substituted or unsubstituted aromatic heterocyclic group and the like) and the like, Rrepresents —NRR(wherein Rand Rmay be the same or different, and each represents a hydrogen atom, substituted or unsubstituted lower alkyl and the like) and the like, Rrepresents —NRR(wherein Rand Rmay be the same or different, and each represents a hydrogen atom, substituted or unsubstituted lower alkyl and the like)] or a pharmaceutically acceptable salt thereof.


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