The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2011
Filed:
Apr. 26, 2007
François Morvan, Castelnau le Lez, FR;
Albert Meyer, Perols, FR;
Jean-jacques Vasseur, Combaillaux, FR;
Sébastien Vidal, Villeurbanne, FR;
Jean-pierre Cloarec, Lyons, FR;
Yann Chevolot, Fleurieux sur l'Arbresle, FR;
Eliane Souteyrand, Chambon sur Cisse, FR;
François Morvan, Castelnau le Lez, FR;
Albert Meyer, Perols, FR;
Jean-Jacques Vasseur, Combaillaux, FR;
Sébastien Vidal, Villeurbanne, FR;
Jean-Pierre Cloarec, Lyons, FR;
Yann Chevolot, Fleurieux sur l'Arbresle, FR;
Eliane Souteyrand, Chambon sur Cisse, FR;
Abstract
Method for the synthesis of nucleotide derivatives wherein molecules of interest are grafted on the oligonucleotide with the help of a 'click chemistry' reaction between an azide function on the molecule of interest and an alkyne function on the oligonucleotide, or between an alkyne function on the molecule of interest and an azide function on the oligonucleotide. Intermediate molecules, notably alkyne functionalized oligonucleotides, grafted oligonucleotides, azide functionalized oligonucleotides, oligonucleotide micro arrays containing them and the use of those grafted oligonucleotides for biological investigation and for cell targeting.