The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2011
Filed:
Jan. 29, 2010
Hironori Harada, Tokyo, JP;
Kazuyuki Hattori, Tokyo, JP;
Kazuya Fujita, Tokyo, JP;
Masataka Morita, Tokyo, JP;
Sunao Imada, Tokyo, JP;
Yoshito Abe, Tokyo, JP;
Hiromichi Itani, Tokyo, JP;
Tatsuaki Morokata, Tokyo, JP;
Hideo Tsutsumi, Osaka, JP;
Hironori Harada, Tokyo, JP;
Kazuyuki Hattori, Tokyo, JP;
Kazuya Fujita, Tokyo, JP;
Masataka Morita, Tokyo, JP;
Sunao Imada, Tokyo, JP;
Yoshito Abe, Tokyo, JP;
Hiromichi Itani, Tokyo, JP;
Tatsuaki Morokata, Tokyo, JP;
Hideo Tsutsumi, Osaka, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
To provide a useful compound as an active ingredient for a preventing and/or treating agent for rejection in the transplantation of an organ, bone marrow, or a tissue, an autoimmune disease, or the like, which has an excellent S1Pagonist activity. Since the compound of the invention has an S1Pagonist activity, it is useful as an active ingredient for a treating or preventing agent for a disease caused by unfavorable lymphocytic infiltration, for example, an autoimmune disease such as graft rejection in the transplantation of an organ, bone marrow, or a tissue, a graft-versus-host disease, rheumatic arthritis, multiple sclerosis, systemic lupus erythematosus, a nephrotic syndrome, encephalomeningitis, myasthenia gravis, pancreatitis, hepatitis, nephritis, diabetes, pulmonary disorder, asthma, atopic dermatitis, inflammatory bowel disease, atherosclerosis, ischemia-reperfusion injury, or an inflammatory disease, and further, a disease caused by the abnormal growth or accumulation of cells such as cancer and leukemia.