The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2011

Filed:

Jun. 24, 2005
Applicants:

Atsuro Nakazato, Tokyo, JP;

Taketoshi Okubo, Tokyo, JP;

Dai Nozawa, Tokyo, JP;

Tomoko Tamita, Tokyo, JP;

Ludo E. J. Kennis, Beerse, BE;

Inventors:

Atsuro Nakazato, Tokyo, JP;

Taketoshi Okubo, Tokyo, JP;

Dai Nozawa, Tokyo, JP;

Tomoko Tamita, Tokyo, JP;

Ludo E. J. Kennis, Beerse, BE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 25/16 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

[PROBLEM TO BE SOLVED] An object of the present invention is to provide an antagonist against CRF receptors and/or an agonist for δ receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastrointestinal diseases, drug dependence, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, pain, etc. [SOLUTION] A pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by the following a [I] has a high affinity for CRF receptors and/or δ receptors, and is effective against diseases in which CRF is considered to be involved.


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