The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2011
Filed:
Apr. 17, 2007
Applicants:
Brian R. Murphy, Bethesda, MD (US);
Peter L. Collins, Bethesda, MD (US);
Mario H. Skiadopoulos, Potomac, MD (US);
Inventors:
Brian R. Murphy, Bethesda, MD (US);
Peter L. Collins, Bethesda, MD (US);
Mario H. Skiadopoulos, Potomac, MD (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/155 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides isolated nucleic acids encoding recombinant genomes or antigenomes of Human Parainfluenza Viruses that are useful as vaccines. The recombinant genomes or antigenomes can be incorporated into expression vectors for production of recombinant viruses in vitro. The invention also provides recombinant Human Parainfluenza viruses having one or more mutations that attenuate replication of the virus in a host.