The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2011

Filed:

Mar. 29, 2005
Applicants:

Dominique Swinnen, Beaumont, FR;

Catherine Jorand-lebrun, Contamine-Sarzin, FR;

Patrick Gerber, Etoy, CH;

Jerome Gonzalez, Annemasse, FR;

Agnes Bombrun, Chambesy, CH;

Inventors:

Dominique Swinnen, Beaumont, FR;

Catherine Jorand-Lebrun, Contamine-Sarzin, FR;

Patrick Gerber, Etoy, CH;

Jerome Gonzalez, Annemasse, FR;

Agnes Bombrun, Chambesy, CH;

Assignee:

Merck Serono SA, Vaud, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 333/34 (2006.01); C07C 65/03 (2006.01); C07C 211/44 (2006.01); C07C 233/65 (2006.01); C07C 311/15 (2006.01); A61K 31/165 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is related to carboxylic acids of Formula (I) and use thereof for the treatment and/or prevention of obesity and/or metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance, insulin resistance, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, polycystic ovary syndrome (PCOS). In particular, the present invention is related to the use of carboxylic acids of Formula (I) to modulate, notably to inhibit the activity of PTPs.


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