The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2011

Filed:

Oct. 27, 2006
Applicants:

David Hallett, Buckinghamshire, GB;

Craig W. Lindsley, Brentwood, TN (US);

Elizabeth M. Naylor, Needham, MA (US);

Zhijian Zhao, Wilmington, DE (US);

Cory R. Theberge, Elkins Park, PA (US);

Scott E. Wolkenberg, Jenkintown, PA (US);

M. Brad Nolt, Gilbertsville, PA (US);

Inventors:

David Hallett, Buckinghamshire, GB;

Craig W. Lindsley, Brentwood, TN (US);

Elizabeth M. Naylor, Needham, MA (US);

Zhijian Zhao, Wilmington, DE (US);

Cory R. Theberge, Elkins Park, PA (US);

Scott E. Wolkenberg, Jenkintown, PA (US);

M. Brad Nolt, Gilbertsville, PA (US);

Assignee:

Merck, Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); C07D 211/32 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to piperidine compounds that inhibit the glycine transporter GlyT1 and which are useful in the treatment of neurological and psychiatric disorders associated with glycinergic or glutamatergic neurotransmission dysfunction and diseases in which the glycine transporter GlyT1 is involved.


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