The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2011

Filed:

Jun. 20, 2008
Applicants:

Todd Richard Elworthy, Los Altos, CA (US);

Joan Heather Hogg, Sunnyvale, CA (US);

Joshua Kennedy-smith, San Francisco, CA (US);

Counde O'yang, Sunnyvale, CA (US);

Mark Smith, San Francisco, CA (US);

Zachary Kevin Sweeney, Redwood City, CA (US);

Jeffrey Wu, Saratoga, CA (US);

Inventors:

Todd Richard Elworthy, Los Altos, CA (US);

Joan Heather Hogg, Sunnyvale, CA (US);

Joshua Kennedy-Smith, San Francisco, CA (US);

Counde O'Yang, Sunnyvale, CA (US);

Mark Smith, San Francisco, CA (US);

Zachary Kevin Sweeney, Redwood City, CA (US);

Jeffrey Wu, Saratoga, CA (US);

Assignee:

Roche Palo Alto LLC, South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/708 (2006.01); A61K 31/4184 (2006.01); A61K 31/437 (2006.01); A61K 31/5025 (2006.01); A61P 31/18 (2006.01); C07D 235/26 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formula I, wherein R, R, R, X and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.


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