The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2011

Filed:

May. 11, 2007
Applicants:

John A. Brinkman, West Caldwell, NJ (US);

Adrian Wai-hing Cheung, Glen Rock, NJ (US);

Fariborz Firooznia, Florham Park, NJ (US);

Kevin Richard Guertin, Verona, NJ (US);

Nicholas Marcopulos, North Caldwell, NJ (US);

Lida Qi, Leonia, NJ (US);

Jagdish Kumar Racha, Iselin, NJ (US);

Ramakanth Sarabu, Towaco, NJ (US);

Jenny Tan, New Providence, NJ (US);

Jefferson Wright Tilley, North Caldwell, NJ (US);

Inventors:

John A. Brinkman, West Caldwell, NJ (US);

Adrian Wai-Hing Cheung, Glen Rock, NJ (US);

Fariborz Firooznia, Florham Park, NJ (US);

Kevin Richard Guertin, Verona, NJ (US);

Nicholas Marcopulos, North Caldwell, NJ (US);

Lida Qi, Leonia, NJ (US);

Jagdish Kumar Racha, Iselin, NJ (US);

Ramakanth Sarabu, Towaco, NJ (US);

Jenny Tan, New Providence, NJ (US);

Jefferson Wright Tilley, North Caldwell, NJ (US);

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 513/04 (2006.01); A61K 31/519 (2006.01); A61P 3/10 (2006.01); A61P 11/06 (2006.01); A61K 31/4353 (2006.01); A61K 31/496 (2006.01); A61K 31/5355 (2006.01); A61K 31/45 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are presented compounds of the formula or a pharmaceutically acceptable salt thereof, which are active adenosine A2B receptor antagonists and useful in the treatment of diabetes, diabetic retinopathy, asthma and diarrhea.


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