The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2011
Filed:
Oct. 30, 2007
Yvonne Man-yee Chen, San Mateo, CA (US);
Ross G. Clark, Auckland, NZ;
Andrea G. Cochran, San Francisco, CA (US);
Yves Dubaquie, Lawrenceville, NJ (US);
Paul J. Fielder, Redwood City, CA (US);
Ellen Filvaroff, San Francisco, CA (US);
Henry B. Lowman, El Granda, CA (US);
Deborah L. Mortensen, Pacifica, CA (US);
Iain C. A. F. Robinson, St. Albans, GB;
Nicholas J. Skelton, San Mateo, CA (US);
Yvonne Man-Yee Chen, San Mateo, CA (US);
Ross G. Clark, Auckland, NZ;
Andrea G. Cochran, San Francisco, CA (US);
Yves Dubaquie, Lawrenceville, NJ (US);
Paul J. Fielder, Redwood City, CA (US);
Ellen Filvaroff, San Francisco, CA (US);
Henry B. Lowman, El Granda, CA (US);
Deborah L. Mortensen, Pacifica, CA (US);
Iain C. A. F. Robinson, St. Albans, GB;
Nicholas J. Skelton, San Mateo, CA (US);
Genentech, Inc., South San Francisco, CA (US);
Abstract
The present invention relates to a method for the treatment of a cartilage disorder, including cartilage damaged by injury or degenerative cartilagenous disorders. The method involves contacting the cartilage with an IGF-1 analog with altered affinity for IGF-binding proteins (IGFBPs) or an IGFBP displacer peptide that prevents the interaction of an IGF with an IGFBP and does not bind to a human IGF receptor.