The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2011

Filed:

Aug. 29, 2007
Applicants:

Wu MA, Silver Spring, MD (US);

Jinny Lin Liu, Ellicott, MD (US);

Thomas O'shaughnessy, College Park, MD (US);

Inventors:

Wu Ma, Silver Spring, MD (US);

Jinny Lin Liu, Ellicott, MD (US);

Thomas O'Shaughnessy, College Park, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C40B 50/06 (2006.01); C40B 60/04 (2006.01); C12N 5/00 (2006.01); C12N 5/079 (2006.01); A01N 63/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention comprises a method for generating functional neural networks using neural progenitor cells on microelectrode arrays (MEAs). The method involves dissociating neural progenitor cells from an embryo, propagating the neural progenitor cells, passaging the neural progenitor cells and seeding the neural progenitor cells on MEAs to produce a functional neural network. The neural progenitor cells may be continuously passaged to propagate an endless supply of neural progenitor cells. The resultant passaged progenitor cell derived neural network MEA may be used to detect and/or quantify various biological or chemical toxins.


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