The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2011

Filed:

Jun. 02, 2006
Applicants:

Brian David Wolf, Machesney Park, IL (US);

Surbhi Desai, Rockford, IL (US);

Peter T. Czerney, Weimar, DE;

Frank G. Lehmann, Jena, DE;

Bernd G. Schweder, Jena, DE;

Matthias S. Wenzel, Jena, DE;

Inventors:

Brian David Wolf, Machesney Park, IL (US);

Surbhi Desai, Rockford, IL (US);

Peter T. Czerney, Weimar, DE;

Frank G. Lehmann, Jena, DE;

Bernd G. Schweder, Jena, DE;

Matthias S. Wenzel, Jena, DE;

Assignee:

Pierce Biotechnology, Inc., Rockford, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); G01N 33/58 (2006.01); C12Q 1/68 (2006.01); C09B 23/00 (2006.01); C09B 57/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

A hydroxyquinolone compound formulated as a fluorescent dye for protein detection, assay, quantitation, etc. The hydroxyquinolone compound may be modified, for example, by adding or removing sulfate groups, changing hydrocarbon chain lengths, etc. to result in more desirable properties such as enhanced binding to basic proteins, enhanced solubility, etc. The dye has enhanced sensitivity over commercially available protein stains, and may be used to stain proteins in solution, proteins separated on gels, proteins transferred to solid supports, etc. Methods of using the dyes are also disclosed.


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