The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2011

Filed:

Feb. 28, 2006
Applicants:

David S. F. Young, Toronto, CA;

Helen P. Findlay, Toronto, CA;

Susan E. Hahn, Toronto, CA;

Lisa M. Cechetto, Ancaster, CA;

Fortunata Mcconkey, Shelburne, CA;

Inventors:

David S. F. Young, Toronto, CA;

Helen P. Findlay, Toronto, CA;

Susan E. Hahn, Toronto, CA;

Lisa M. Cechetto, Ancaster, CA;

Fortunata McConkey, Shelburne, CA;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/16 (2006.01); C12N 15/00 (2006.01); A61K 39/395 (2006.01); A61K 30/00 (2006.01); C12P 21/08 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMAB of the instant invention.


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