The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2011
Filed:
Sep. 07, 2007
Applicants:
James A. Ernst, San Francisco, CA (US);
Paul Polakis, Mill Valley, CA (US);
Bonnee Rubinfeld, Danville, CA (US);
Venita I. Dealmeida, San Carlos, CA (US);
Inventors:
James A. Ernst, San Francisco, CA (US);
Paul Polakis, Mill Valley, CA (US);
Bonnee Rubinfeld, Danville, CA (US);
Venita I. DeAlmeida, San Carlos, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/01 (2006.01); A61K 38/00 (2006.01); C07K 19/00 (2006.01); A61K 39/385 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides for chimeric Wnt antagonists comprising a Frz domain component derived from a Frizzled protein, a secreted Frizzled related protein or Ror protein and an Fc immunoglobulin component, and their use in the treatment and diagnostic detection of cellular Wnt signaling and Wnt-mediated disorders, including cancer.