The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2011
Filed:
Nov. 16, 2006
Xiao-dong Xiang, Danville, CA (US);
Gang Wang, Martinez, CA (US);
Haitao Yang, San Jose, CA (US);
Jonathan Melman, San Mateo, CA (US);
Gerald Francis Dionne, Winchester, MA (US);
Xiao-Dong Xiang, Danville, CA (US);
Gang Wang, Martinez, CA (US);
Haitao Yang, San Jose, CA (US);
Jonathan Melman, San Mateo, CA (US);
Gerald Francis Dionne, Winchester, MA (US);
Intematix Corporation, Fremont, CA (US);
Abstract
Embodiments of the present invention are generally related to apparatus and methodology of thermal applicators in cancer therapy. In particular, the present embodiments are directed to a technique called 'nanoparticle ferromagnetic resonance heating,' where ferromagnetic resonance heating in addition to an RF hyperthermia treatment is used to cause cell apoptosis and necrosis. An apparatus for carrying out a ferromagnetic resonance heating treatment of a tumor, comprises a volume concentration of super paramagnetic particles contained within the interior of the tumor, the concentration ranging from about 0.1 to about 1 percent; a magnetic field source configured to deliver a gradient DC magnetic field to the region of the tumor; and an energy source configured to deliver to the tumor an RF field at a frequency ranging from about 100 to 200 MHz. The apparatus of claim, wherein the super paramagnetic particles are selected from the group consisting of maghemite (γ-FeO) based compounds, and yttrium iron garnet (YFeO) based compounds.