The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2011

Filed:

Jul. 21, 2006
Applicants:

Satyanarayana Chava, Secunderabad, IN;

Seeta Ramanjaneyulu Gorantla, Secunderabad, IN;

Ramdas Chavakula, Secunderabad, IN;

Babu Rao Konudula, Secunderabad, IN;

Inventors:

Satyanarayana Chava, Secunderabad, IN;

Seeta Ramanjaneyulu Gorantla, Secunderabad, IN;

Ramdas Chavakula, Secunderabad, IN;

Babu Rao Konudula, Secunderabad, IN;

Assignee:

Matrix Laboratories Limited, Secunderabad, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention encompasses a method for the preparation of Almotriptan and its pharmaceutically acceptable salts comprises, i) Methylation of 3-[5-(1-Pyrrolidinyl sulfonyl methyl)1H-indol-yl]ethane amine ii) Treating crude Almotriptan with a hydroxy benzoic acid yields hydroxy benzoic acid addition salt of Almotriptan iii) Converting Almotriptan hydroxy benzoic acid addition salt to Almotriptan and iv) Salification of Almotriptan to its pharmaceutically acceptable salts.


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