The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2011

Filed:

Jan. 24, 2007
Applicants:

Vladimir Naddaka, Petch-Tikva, IL;

Eyal Klopfer, Tel Aviv, IL;

Shady Saeed, Haifa, IL;

Stephen Cherkez, Caesarea, IL;

Oded Arad, Rehovot, IL;

Inventors:

Vladimir Naddaka, Petch-Tikva, IL;

Eyal Klopfer, Tel Aviv, IL;

Shady Saeed, Haifa, IL;

Stephen Cherkez, Caesarea, IL;

Oded Arad, Rehovot, IL;

Assignee:

Chemagis Ltd., Bnei Brak, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided is a process for producing highly pure 4-amino-1-isobutyl-1H-imidazo[4,5-c]quinoline (imiquimod), which includes reacting 4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline with a non-gaseous amine precursor. Also provided are methods for isolating highly pure imiquimod. Further provided are intermediates useful in the production of imiquimod, methods for producing such intermediates, and methods for obtaining imiquimod from such intermediates.


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