The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2011

Filed:

Mar. 26, 2009
Applicants:

Michael D. Shultz, Stow, MA (US);

Christine Hiu-tung Chen, Waltham, MA (US);

Young Shin Cho, Cambridge, MA (US);

Lei Jiang, Waltham, MA (US);

Jianmei Fan, Newton, MA (US);

Gang Liu, Waltham, MA (US);

Dyuti Majumdar, Cambridge, MA (US);

Jianke LI, Cambridge, MA (US);

Inventors:

Michael D. Shultz, Stow, MA (US);

Christine Hiu-Tung Chen, Waltham, MA (US);

Young Shin Cho, Cambridge, MA (US);

Lei Jiang, Waltham, MA (US);

Jianmei Fan, Newton, MA (US);

Gang Liu, Waltham, MA (US);

Dyuti Majumdar, Cambridge, MA (US);

Jianke Li, Cambridge, MA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4162 (2006.01); A61K 31/4155 (2006.01); C07D 487/04 (2006.01); C07D 231/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present teachings relate to compounds of Formula I: and pharmaceutically acceptable salts, hydrates, esters, and prodrugs thereof, wherein R, R, R, Y, Z, andare as defined herein. The present teachings also provide methods of preparing compounds of Formula I and methods of using compounds of Formula I in treating, inhibiting, or preventing pathologic conditions or disorders mediated wholly or in part by deacetylases.


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