The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2011
Filed:
Dec. 20, 2005
Applicants:
Doriana Froim, Cambridge, MA (US);
John M. Essigmann, Cambridge, MA (US);
Martin G. Marinus, West Boylston, MA (US);
Inventors:
Doriana Froim, Cambridge, MA (US);
John M. Essigmann, Cambridge, MA (US);
Martin G. Marinus, West Boylston, MA (US);
Assignees:
Massachusetts Institute of Technology, Cambridge, MA (US);
University of Massachusetts, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A01N 55/02 (2006.01); A01N 33/00 (2006.01); A01N 33/18 (2006.01); A01N 33/24 (2006.01); A61K 31/65 (2006.01); A61K 31/28 (2006.01); A61K 31/13 (2006.01); A61K 31/16 (2006.01); A61K 31/04 (2006.01); A61K 33/24 (2006.01); C07C 43/00 (2006.01); C07C 49/00 (2006.01); C07C 237/26 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention provides methods and pharmaceutical compositions for treating a subject having a condition associated with an antibiotic resistant bacterial infection. The invention includes administering to a subject a therapeutically effective combination of an antibiotic and a toxic compound (e.g., a nucleic acid damaging agent, an alkylating agent, or a heavy metal containing compound).