The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2011

Filed:

May. 11, 2007
Applicants:

Yuan-tsong Chen, Taipei, TW;

Shuen-iu Hung, Taipei, TW;

Chih-lung Shen, Taipei, TW;

Chi-feng Chang, Taipei, TW;

Hsin-yu Lin, Taipei, TW;

Wei-hsuan Chen, LiouJia Township, TW;

Inventors:

Yuan-Tsong Chen, Taipei, TW;

Shuen-Iu Hung, Taipei, TW;

Chih-Lung Shen, Taipei, TW;

Chi-Feng Chang, Taipei, TW;

Hsin-Yu Lin, Taipei, TW;

Wei-Hsuan Chen, LiouJia Township, TW;

Assignees:

Pharmigene Inc., Taipei, TW;

Academia Sinica, Taipei, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to a method of determining the presence of certain HLA alleles, such as HLA-B*1502 or HLA-B*5801, and a kit for carrying out this method. Also disclosed is a method for assessing whether a patient is at risk for developing adverse drug reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis, or hypersensitivity syndrome) based on the presence or absence of a genetic marker (e.g., HLA-B*1502, HLA-B*5801, or HLA-B*4601).


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