The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 17, 2011
Filed:
Oct. 07, 2008
Helen Rachel Crooke, Wokingham, GB;
Jacqueline Elizabeth Shea, Wokingham, GB;
Robert Graham Feldman, Wokingham, GB;
Sylvain Gabriel Goutebroze, Lyons, FR;
Francois-xavier Le Gros, Saint Genis Laval, FR;
Helen Rachel Crooke, Wokingham, GB;
Jacqueline Elizabeth Shea, Wokingham, GB;
Robert Graham Feldman, Wokingham, GB;
Sylvain Gabriel Goutebroze, Lyons, FR;
Francois-Xavier Le Gros, Saint Genis Laval, FR;
Merial Limited, Duluth, GA (US);
Abstract
Disclosed and claimed are a mutant of a gram negative bacterium, wherein said bacterium has at least one mutation in a nucleotide sequence which codes for a polypeptide having an identity which is equal or more than 70%, 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98%, or 99% with an amino acid sequence coded by a nucleotide sequence selected from the group consisting of nucleotide sequences identified SEQ ID NO: 2, 6, 9, 12, 16, 19, 22, 25, 28, 31, 34, 37, 40, 43, 46, 49, 52, 55, 58, 61, 64, 67, 70, 75, 78, 81, 84, 87, 90, 93; said mutation resulting in attenuated virulence of the bacterium. Immunogenic compositions and vaccines containing such a mutant are also disclosed and claimed.