The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2011
Filed:
Mar. 29, 2006
Applicants:
Kunihiko Higashiura, Hyogo, JP;
Takashi Ogino, Hyogo, JP;
Kazuhito Furukawa, Hyogo, JP;
Inventors:
Assignee:
Nippon Zoki Pharmaceutical Co., Ltd., Osaka, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); A61K 31/165 (2006.01); A61K 31/44 (2006.01); C07D 213/81 (2006.01); C07D 211/30 (2006.01); C07D 211/82 (2006.01); C07C 233/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed is a novel benzyloxypropylamine derivative having an excellent tachykinin receptor antagonistic effect. This compound shows a good transfer into the blood and a long blood half-life in the blood kinetic test using a guinea pig orally administered with the compound and is stable in an animal plasma. The compound also shows a high transfer to the central nervous system when it is orally administered to a guinea pig at a certain dose. Accordingly, the benzyloxypropylamine derivative is quite useful as a novel anti-tachykinin agent.