The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2011

Filed:

May. 15, 2007
Applicants:

David C. Tully, San Diego, CA (US);

Arnab K. Chatterjee, Encinitas, CA (US);

Hank Michael James Petrassi, Cardiff, CA (US);

Badry Bursulaya, San Diego, CA (US);

Glen Spraggon, San Diego, CA (US);

Inventors:

David C. Tully, San Diego, CA (US);

Arnab K. Chatterjee, Encinitas, CA (US);

Hank Michael James Petrassi, Cardiff, CA (US);

Badry Bursulaya, San Diego, CA (US);

Glen Spraggon, San Diego, CA (US);

Assignee:

IRM LLC, Hamilton, BM;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); C07D 403/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.


Find Patent Forward Citations

Loading…