The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2011
Filed:
Mar. 04, 2008
Amala Kishan Kompella, Hyderabad, IN;
Bhujanga Rao Adibhatla Kali Satya, Hyderabad, IN;
Sreenivas Rachakonda, Hyderabad, IN;
Nannapaneni Venkaiah Chowdary, Hyderabad, IN;
Amala kishan Kompella, Hyderabad, IN;
Bhujanga rao Adibhatla Kali Satya, Hyderabad, IN;
Sreenivas Rachakonda, Hyderabad, IN;
Nannapaneni Venkaiah Chowdary, Hyderabad, IN;
Natco Pharma Limited, Hyderabad, IN;
Abstract
This invention relates to a process for the preparation of (3-trifluoromethylsulfonyl)-N-[4-methyl-3-(4-pyridin-3yl-pyrimidin-2ylamino)-phenyl]-benzamide (formula (I)) starting from 4-methyl-2-nitro-aniline (formula (II)) through intermediates (3-trifluoromethylsulfonyl)-N-[4-methyl-3-nitrophenyl]-benzamide (formula (III)), (3-trifluoromethylsulfonyl)-N-[3-amino-4-methylphenyl]-benzamide (formula (IV)) and (3-trifluoromethylsulfonyl)-N-[3-guanidino-4-methylphenyl]-benzamide (formula (V)). This invention also relates to processes for the preparation of these intermediates. The compound of formula (I), also known as AN-024, is: