The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2011

Filed:

Feb. 20, 2009
Applicants:

Joe Timothy Bamberg, East Palo Alto, CA (US);

Mark Bartlett, Mountain View, CA (US);

Daisy Joe Dubois, Palo Alto, CA (US);

Todd Richard Elworthy, Los Altos, CA (US);

Robert Than Hendricks, San Carlos, CA (US);

Johannes Cornelius Hermann, San Francisco, CA (US);

Rama K. Kondru, Sunnyvale, CA (US);

Remy Lemoine, San Francisco, CA (US);

Yan Lou, San Jose, CA (US);

Timothy D. Owens, Mountain View, CA (US);

Jaehyeon Park, Sunnyvale, CA (US);

David Bernard Smith, San Mateo, CA (US);

Michael Soth, Milpitas, CA (US);

Hanbiao Yang, Sunnyvale, CA (US);

Calvin Wesley Yee, Daly City, CA (US);

Inventors:

Joe Timothy Bamberg, East Palo Alto, CA (US);

Mark Bartlett, Mountain View, CA (US);

Daisy Joe DuBois, Palo Alto, CA (US);

Todd Richard Elworthy, Los Altos, CA (US);

Robert Than Hendricks, San Carlos, CA (US);

Johannes Cornelius Hermann, San Francisco, CA (US);

Rama K. Kondru, Sunnyvale, CA (US);

Remy Lemoine, San Francisco, CA (US);

Yan Lou, San Jose, CA (US);

Timothy D. Owens, Mountain View, CA (US);

Jaehyeon Park, Sunnyvale, CA (US);

David Bernard Smith, San Mateo, CA (US);

Michael Soth, Milpitas, CA (US);

Hanbiao Yang, Sunnyvale, CA (US);

Calvin Wesley Yee, Daly City, CA (US);

Assignee:

Roche Palo Alto, Palo Alto, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables Q and R are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.


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