The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2011
Filed:
Apr. 13, 2006
Luigi DE Ambrosi, Santhià, IT;
Sergio Gonella, Santhià, IT;
Donata Bensi, Vercelli, IT;
Giangiacomo Torri, Milan, IT;
Antonella Bisio, Pavia, IT;
Elena Vismara, Milan, IT;
Luigi De Ambrosi, Santhià, IT;
Sergio Gonella, Santhià, IT;
Donata Bensi, Vercelli, IT;
Giangiacomo Torri, Milan, IT;
Antonella Bisio, Pavia, IT;
Elena Vismara, Milan, IT;
Laboratori Derivati Organici SpA, Milan, IT;
Abstract
The present invention is directed to a multistep process for the physical depolymerization of heparin wherein heparin is subjected to at least two γ-ray irradiations and wherein between two irradiation steps the depolymerised heparin is subjected to a separation step and only a fraction of the depolymerised heparin obtained from the first irradiation is subjected to the second irradiation step. It is also directed to heparin-derived oligosaccharide fractions obtainable by the process of the invention.