The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2011

Filed:

Apr. 12, 2005
Applicants:

Sandra Waugh Ruggles, South San Franciso, CA (US);

Jack Nguyen, South San Franciso, CA (US);

Inventors:

Sandra Waugh Ruggles, South San Franciso, CA (US);

Jack Nguyen, South San Franciso, CA (US);

Assignee:

Catalyst Biosciences, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

MT-SP1 mutein proteases with altered specificity for the target molecules they cleave can be used to treat human diseases, such as cancer. Cleaving VEGF or VEGFR at certain substrate sequences with wild-type and mutein MT-SP1 proteases can be used to treat pathologies associated with angiogenesis.


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