The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2011

Filed:

Sep. 03, 2008
Applicants:

Show-wen Liu, Shetou Township, Changhua County, TW;

Tsyh-lang Lin, Bade, TW;

Cheng-fang Hsu, Toufen Township, Miaoli County, TW;

Cheng-hsien Lin, Taipei, TW;

Tsai-yueh Luo, Longtan Township, Taoyuan County, TW;

Lie-hang Shen, Jhongli, TW;

Haw-jan Chen, Taoyuan, TW;

Inventors:

Show-Wen Liu, Shetou Township, Changhua County, TW;

Tsyh-Lang Lin, Bade, TW;

Cheng-Fang Hsu, Toufen Township, Miaoli County, TW;

Cheng-Hsien Lin, Taipei, TW;

Tsai-Yueh Luo, Longtan Township, Taoyuan County, TW;

Lie-Hang Shen, Jhongli, TW;

Haw-Jan Chen, Taoyuan, TW;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 207/46 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound containing carboxylate ester and N2S2 ligand bi-functional groups and a manufacturing method thereof are disclosed. The S in the N2S2 ligand of the compound containing carboxylate ester and N2S2 ligand bi-functional groups includes a protective group so as to avoid to be oxidized and easy storage. In a complex reaction, the protective group is automatically released As to the active carboxylate ester, it is for reacting with compounds having amino groups such as amines, amino acids, peptides, or protein etc while the N2S2 ligand is for bonding with technetium or rhenium so as to form neutral complex. The compound containing carboxylate ester and N2S2 ligand bi-functional groups is applied to radiopharmaceuticals such as contrast agents for tissues and target agents.


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