The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2011

Filed:

Oct. 13, 2006
Applicants:

Yi-heng Chen, Whippany, NJ (US);

Zhijian LU, Clinton, NJ (US);

Peter J. Sinclair, Scotch Plains, NJ (US);

Inventors:

Yi-Heng Chen, Whippany, NJ (US);

Zhijian Lu, Clinton, NJ (US);

Peter J. Sinclair, Scotch Plains, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 47/10 (2006.01); A61K 31/27 (2006.01); C07C 331/00 (2006.01); C07C 381/00 (2006.01); C07C 333/00 (2006.01); C07C 261/00 (2006.01); C07C 269/00 (2006.01); C07C 271/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds having a biphenyl group substituted with a phenyl or heteroaromatic group, as shown in Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis:


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