The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2011
Filed:
Jul. 16, 2007
Fang-tsao Hong, Thousand Oaks, CA (US);
Kelvin K. C. Sham, Thousand Oaks, CA (US);
Seifu Tadesse, Simi Valley, CA (US);
Andrew Tasker, Simi Valley, CA (US);
Fang-Tsao Hong, Thousand Oaks, CA (US);
Kelvin K. C. Sham, Thousand Oaks, CA (US);
Seifu Tadesse, Simi Valley, CA (US);
Andrew Tasker, Simi Valley, CA (US);
Amgen Inc., Thousands Oaks, CA (US);
Abstract
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of pro-inflammatory cytokine mediated diseases, including inflammation and related conditions. The compounds have a general Formula I wherein s, T, R, R, Rand Rare defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, methods of use such as treatment of p38 mediated diseases by administering the compounds of Formula I or compositions including the compounds of Formula I, and intermediates and processes useful for the preparation of compounds of Formula I.