The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2011
Filed:
Apr. 30, 2002
Timothy J. O'brien, Little Rock, AR (US);
Martin J. Cannon, Little Rock, AR (US);
Alessandro Santin, Little Rock, AR (US);
Timothy J. O'Brien, Little Rock, AR (US);
Martin J. Cannon, Little Rock, AR (US);
Alessandro Santin, Little Rock, AR (US);
Board of Trustees of the University of Arkansas, Little Rock, AR (US);
Abstract
The disclosed nucleic acid primer sets, used in combination with quantitative amplification (PCR) of tissue cDNA, can indicate the presence of specific proteases in a tissue sample. Specifically, the present invention relates to expression of hepsin protease. The detected proteases are themselves specifically over-expressed in certain cancers, and the presence of their genetic precursors may serve for early detection of associated ovarian and other malignancies, and for the design of interactive therapies for cancer treatment.