The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2011
Filed:
Nov. 28, 2007
Peter B. Dervan, San Marino, CA (US);
Claire S. Jacobs, San Marino, CA (US);
Nicholas G. Nickols, Van Nuys, CA (US);
Daniel A. Harki, Pasadena, CA (US);
Peter B. Dervan, San Marino, CA (US);
Claire S. Jacobs, San Marino, CA (US);
Nicholas G. Nickols, Van Nuys, CA (US);
Daniel A. Harki, Pasadena, CA (US);
California Institute of Technology, Pasedena, CA (US);
Abstract
The present invention relates to polyamides with a tail comprising a linker and an end-group. A preferred end-group is isophthalic acid and derivatives thereof. Polyamides of the invention are capable of entering the nucleus of cells. Polyamides of the invention are capable of selectively binding DNA. The invention also relates to methods of using the polyamides in therapy and research.