The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7935500 B1

PDF
Full Text
Expired
Date of Patent:
May. 03, 2011

Filed:

Mar. 26, 2003
Applicants:

David J. Gerber, Somerville, MA (US);

Maria Karayiorgou, Riverdale, NY (US);

Tsuyoshi Miyakawa, Aichi, JP;

Susumu Tonegawa, Chestnut Hill, MA (US);

Inventors:

David J. Gerber, Somerville, MA (US);

Maria Karayiorgou, Riverdale, NY (US);

Tsuyoshi Miyakawa, Aichi, JP;

Susumu Tonegawa, Chestnut Hill, MA (US);

Assignees:

Massachusetts Institute of Technology, Cambridge, MA (US);

Rockefeller University, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/34 (2006.01); C12Q 1/68 (2006.01); C12Q 1/02 (2006.01); G01N 33/53 (2006.01); G01N 33/15 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides targets, methods, and reagents for the diagnosis and treatment of schizophrenia and related conditions. The invention provides methods for the diagnosis of schizophrenia and susceptibility to schizophrenia by detection of polymorphisms, mutations, variations, alterations in expression, etc., in calcineurin genes or calcineurin interacting genes, or polymorphisms linked to such genes. The invention provides oligonucleotides, arrays, and antibodies for detection of polymorphisms and variants. The invention provides transgenic mice having alterations in such genes. The invention also provides methods of treating schizophrenia by administering compounds that target these genes. The invention further provides screening methods for identifying such compounds and compounds obtained by performing the screens.


Find Patent Forward Citations

Gerber, David. (2011). Identifying calcineurin activators for treatment of schizophrenia (U.S. Patent No. 7935500). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7935500

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