The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2011
Filed:
Nov. 13, 2007
Mario Alberto Flores-valdez, Jalisco, MX;
Gary K. Schoolnik, Palo Alto, CA (US);
Michel Klein, Zaandijk, NL;
Jerald C. Sadoff, Washington, DC (US);
David Hone, Poolesville, MD (US);
Mario Alberto Flores-Valdez, Jalisco, MX;
Gary K. Schoolnik, Palo Alto, CA (US);
Michel Klein, Zaandijk, NL;
Jerald C. Sadoff, Washington, DC (US);
David Hone, Poolesville, MD (US);
Aeras Global TB Vaccine Foundation, Rockville, MD (US);
The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);
Abstract
A vaccine for treating or preventing the establishment of latent tuberculosis infections is provided. The vaccine comprises a recombinantthat overexpresses the transcription factor DosR, at a level sufficient to induce production of the dosR regulon genes or proteins. A host to whom the vaccine is administered mounts an immune response to the dosR regulon proteins and is thus protected from the establishment, persistence or reactivation of latent tuberculosis.